Health-related burden of illness associated with excessive daytime sleepiness in patients with obstructive sleep apnea compliant with continuous positive airway pressure treatment

Grandner M, Stack C, Min j, Saad R, Leary EB, Eldemir L, Hyman D. Health-related burden of illness associated with excessive daytime sleepiness in patients with obstructive sleep apnea compliant with continuous positive airway pressure treatment. CHEST, Vol 160, Issue 4, Supplement A2419-A2420, October 01, 2021. DOI: 10.1016/j.chest.2021.07.2092.

AbstractsEileen LearyCV
Living to Dream - Reply JAMA Neurology

Read our thoughtful response to the editorial “Should Neurologists Be Concerned With REM Sleep Quantity?” written about our 2020 REM/Mortality study in JAMA Neurology.

Article: https://jamanetwork.com/journals/jamaneurology/article-abstract/2776791

Leary EB, Stone KL, Mignot E., Living to Dream - Reply JAMA Neurol. April 1, 2021. JAMA Neurol. 2021;78(4):495-496. DOI: 10.1001/jamaneurol.2021.0056. PMID: 33646274.

The Snooze Button (Podcast)
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Had a great discussion with Neil Hedley from the Snooze Button Podcast.

Our conversation started with my research on REM and mortality but we covered a range of topics including wearables, CBD, and best of all -- sleep nerd fights.

Neil’s podcast is an entertaining and educational medium for learning about the science of sleep as he engages with a range of guests in an effort to better understand his own sleep problems.

Link to Podcast: https://thesnoozebutton.com/the-rem-sleep-youre-not-getting-could-be-killing-you

Reduced REM Sleep is Associated with Mortality in Middle Aged and Older Adults
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We investigated whether REM sleep is associated with greater risk of mortality in 2 independent cohorts and explored whether another sleep stage could be driving the findings.

This cross-sectional study from 2 independent cohorts found lower amounts of REM sleep were associated with increased risk of all-cause mortality. There was a 13% higher mortality rate over 12.1 years for every 5% reduction in REM sleep in a cohort of 2675 older men, and the finding was replicated in a cohort of 1375 middle-aged men and women followed-up for 20.8 years.

Article: https://jamanetwork.com/journals/jamaneurology/article-abstract/2767713

Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman S, Mignot E, Stone KL for the Osteoporotic Fractures in Men (MrOS) Study Research Group. Reduced REM Sleep is Associated with Mortality in Middle Aged and Older Adults. JAMA Neurol. Published online July 6, 2020. DOI:10.1001/jamaneurol.2020.2108. PMID: 32628261.

Design of a deep learning model for automatic scoring of periodic and non-periodic leg movements during sleep validated against multiple human experts

Carvellia L, Olesen AN, Brink-Kaera A, Leary EB, Peppard PE, Mignot E, Sørensen HBD, Jennum PJ. Design of a deep learning model for automatic scoring of periodic and non-periodic leg movements during sleep validated against multiple human experts. Sleep Medicine, 2020 May: 109-119. DOI: 10.1016/j.sleep.2019.12.032.