Bae C, Zee P, Leary EB, Macfadden W, Fuller DS, Candler S, Husain A. Treatment Satisfaction and Preferences in People With Narcolepsy Transitioning From Sodium Oxybate to Lower-Sodium Oxybate. Sleep 46(suppl_1) A268, May 2023, DOI: 10.1093/sleep/zsad077.0611.
Nichols D, Macfadden W, Leary EB, Gwadry-Sridhar F, Owens J. Hybrid Decentralized Recruitment Approach to a Rare Disease Registry for Pediatric Patients With Narcolepsy: The CATNAP® Registry. Sleep 46(suppl_1) A260-A261, May 2023, DOI: 10.1093/sleep/zsad077.0594.
Leary EB, Bujanover S, Zhang J, Jaeger J, Van Dongen H. Trial design: Solriamfetol’s effect on cognitive Health in Apnea participants during a Randomized Placebo-controlled study (SHARP). Sleep Medicine, Volume 100, Suppl 1, S285-S286 Dec 2022, DOI: 10.1016/j.sleep.2022.05.771.
Leary EB, Kirby T, Skowronski R, Xu K, Pfister C, Macfadden W. Effectiveness and Treatment Optimization Among Participants With Narcolepsy Switching From Sodium Oxybate to Lower-Sodium Oxybate: Interim Data From the SEGUE Study. Sleep 45(suppl_1) A177, June 2022, DOI: 10.1093/sleep/zsac079.392.
Leary EB, Zee P, Fuller DS, Macfadden W, Steininger T, Bae C, Husain AM. Efficacy and Safety in People With Narcolepsy Transitioning From Sodium Oxybate to Lower-Sodium Oxybate: Data From the Real-World TENOR Study. Sleep 45(suppl_1) A176-177, June 2022, DOI: 10.1093/sleep/zsac079.391.
Husain A, Leary EB, Fuller DS, Macfadden W, Whalen M, Bae C, Zee P. Dosing and Reasons for Transitioning From Sodium Oxybate to Lower-Sodium Oxybate in People With Narcolepsy: Data From the Real-World TENOR Study. Sleep 45(suppl_1) A174, June 2022, DOI: 10.1093/sleep/zsac079.385.
Van Dongen H, Dronamraju N, Macfadden W, Leary EB. Baseline characteristics: Solriamfetol’s effect on cognitive Health in Apnea participants during a Randomized Placebo-controlled study (SHARP). Sleep 45(suppl_1) A332, June 2022, DOI: 10.1093/sleep/zsac079.758.
Macfadden W, Leary EB, Gwadry-Sridhar F, Owens J. Children, Adolescents, and Their providers: the Narcolepsy Assessment Partnership (CATNAP™) Pediatric Narcolepsy Registry: Baseline Demographics. Sleep 45(suppl_1) A172-173, June 2022, DOI: 10.1093/sleep/zsac079.382.
Brink-Kjær A, Leary EB, Sund H, Westover MB, Stone KL, Peppard PE, Lane N, Cawthone PM, Redline S, Jennum P, Mignot E, Sorensen HBD. Age Estimation from Sleep using Deep Learning Predicts Life Expectancy. Sleep 45(suppl_1) A143-144, June 2022, DOI: 10.1093/sleep/zsac079.317.
Cederberg KL, Hanif U, Leary EB, Schneider L Morse AM, Blackman A, Schweitzer P, Kotagal S, Bogan R, Kushida CA, Mignot E. Proteomic Biomarkers of Obstructive Sleep Apnea. Sleep 45(suppl_1) A326, June 2022, DOI: 10.1093/sleep/zsac079.744.
Cederberg KL, Hanif U, Leary EB, Schneider L Morse AM, Blackman A, Schweitzer P, Kotagal S, Bogan R, Kushida CA, Mignot E. Proteomic Approach for Understanding the Mechanisms of Periodic Limb Movements and Restless Legs Syndrome. Sleep 45(suppl_1) A244, June 2022, DOI: 10.1093/sleep/zsac079.551.
Grandner M, Stack C, Min j, Saad R, Leary EB, Eldemir L, Hyman D. Health-related burden of illness associated with excessive daytime sleepiness in patients with obstructive sleep apnea compliant with continuous positive airway pressure treatment. CHEST, Vol 160, Issue 4, Supplement A2419-A2420, October 01, 2021. DOI: 10.1016/j.chest.2021.07.2092.
Hanif U, Paulsen RR, Leary EB, Mignot E, Jennum P, Sorensen HBD. Prediction of Patient Demographics using 3D Craniofacial Scans and Multi-view CNNs. Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:1950-1953. DOI: 10.1109/EMBC44109.2020.9176333. PMID: 33018384.
Validated a novel scale to evaluate both “active” sleepiness and “passive” sleepiness using questions that reflect modern life.
This study compared the Situational Sleepiness Scale (SSS) to the Epworth Sleepiness Scale (ESS), which is the current standard to assess sleepiness. The scores were highly correlated (rs=0.72) in a sample of 22 Stanford Sleep Medicine patients and 34 healthy controls. We believe the SSS is a can provide more nuanced picture regarding patient’s overall sleepiness, especially while driving and should be evaluated in a wider population.
Singh CT, Leary EB, Mignot E, Stone KL. Validation of the Situational Sleepiness Scale (SSS). Sleep 43(suppl_1), April 2020 (Late Breaking Abstracts).
In-depth analysis of the relationship between REM and mortality.
Abstract published in SLEEP summarizing the one hundred and two pages painstakingly researched and written for my PhD in Epidemiology and Clinical Research from Stanford University. An exciting story involving multiple cohorts, machine learning, and meta-analysis will keep you on the edge of your seat!
Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman S, Mignot E, Stone KL. The Association Between REM Sleep and Mortality in Three Independent Cohorts. Sleep 43(suppl_1) A19, April 2020.